منابع مشابه
Microtubules get early release
n page 765, Ohzeki et al. present evidence for sequence specificity in assembling chromatin at mammalian centromeres. The sequence requirements imply that construction of centromeric chromatin is more than an epigenetic process. O Centromeric chromatin assembles at AT-rich repeats called ␣ satellite sequences, or alphoids. Type I alphoids contain boxes for the binding of CENP-B, one of several ...
متن کاملMicrotubules get a name
rom the mists of early electron microscopy (EM) images there gradually emerged, during the 1950s and 1960s, long, rod-shaped structures. Various investigators missed them, dismissed them, or called them canaliculi, endoplasmic reticulum, or filamentous elements. Finally Slautterback (1963) and Ledbetter and Porter (1963) gave them a full description, recognized their ubiquity, and bestowed thei...
متن کاملMicrotubules get dynamic
M icrotubules were seen fi rst as static struts in EM images (see " Microtubules get a name " < a r t r e f v o l = " 1 6 8 " p g = " 8 5 2 " > JCB 168:852< / a r t r e f >) and then as polymers created from a defi ned protein component (see " The discovery of tubulin " < a r t r e f v o l = " 1 6 9 " p g = " 5 5 2 " > JCB 169:552< / a r t r e f >). It took a series of studies in the 1980s to e...
متن کاملHow microtubules get fluorescent speckles.
The dynamics of microtubules in living cells can be seen by fluorescence microscopy when fluorescently labeled tubulin is microinjected into cells, mixing with the cellular tubulin pool and incorporating into microtubules. The subsequent fluorescence distribution along microtubules can appear "speckled" in high-resolution images obtained with a cooled CCD camera (Waterman-Storer and Salmon, 199...
متن کاملCytoskeleton: Microtubules get the signal
Investigations of how the cytoskeleton is controlled by Rho GTPase signaling have focused largely on the remodeling of actin. Recent work in fibroblasts shows that microtubules are also subject to regulation by the Rho pathway, and that the signals acting on actin and microtubules can be teased apart.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1595iti5